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750 BCE: Phoenicians found the colony of Motya on Sicily.
734 BCE: Chalcis founds the colony of Naxos on Sicily.
733 BCE: Corinth founds the colony of Syracuse in Sicily.
720 BCE: Chalcis founds the colony of Rhegium in Sicily.
688 BCE: Rhodes and Cretans found Gela in Sicily.
630 BCE: Selinus is founded by colonists from Megara Hyblaea, Sicily.
630 BCE: Messana founds the colony of Himera on Sicily.
580 BCE - 376 BCE: Carthage and Greece fight for dominance in Sicily.
580 BCE - 576 BCE: War between the Sicilian city-states of Segesta and Selinus.
580 BCE - 560 BCE: The main temple of the acropolis, Temple C, was built at Selinus.
580 BCE: Agrigento in Sicily is founded by colonists from Gela, Crete and Rhodes.
570 BCE - 549 BCE: The tyrant Phalaris rules Agrigento, expanding its territory.
491 BCE - 478 BCE: Gelon is tyrant of Syracuse.
489 BCE - 473 BCE: The tyrant Theron rules Agrigento.
480 BCE: Tyrant of Syracuse Gelon defeats the Carthaginians at the battle of Himera.
480 BCE: Agrigento defeats Carthage at the battle of Himera.
480 BCE: The huge temple of Zeus is built at Agrigento.
478 BCE - 467 BCE: Hiero I is tyrant of Syracuse.
458 BCE: A treaty of cooperation is signed between the Sicilian city-state of Segesta and Athens.
450 BCE - 430 BCE: The Temple of Concordia is built at Agrigento.
416 BCE: War breaks out again between rival Sicilian city-states Segesta and Selinus.
415 BCE - 413 BCE: Athenian expedition to attack Syracuse.
415 BCE: Alcibiades persuades the Athenian assembly to send a military expedition to Sicily.
415 BCE: Athens launches an expedition against Sicily, the pretext being protection of Segesta.
414 BCE: The Athenian expedition in Sicily ends in disastrous defeat and the Athenian generals Nikias and Demosthenes are executed.
413 BCE: Agrigento remains neutral in the war between Athens and Syracuse.
409 BCE: Selinus on Sicily is sacked by Hannibal.
406 BCE: Agrigento is attacked and destroyed by Carthage.
405 BCE: Dionysius becomes tyrant in Syracuse, Sicily.
398 BCE - 380 BCE: Plato travels in Egypt, Cyrene, Italy, Syracuse and Sicily.
396 BCE: The Carthaginian city of Lilybaeum is founded on Sicily.
367 BCE: Dionysius II becomes tyrant of Syracuse, Sicily.
356 BCE: Dion becomes tyrant of Syracuse.
344 BCE: Timoleon establishes an oligarchy in Syracuse.
317 BCE: Agathocles takes power in Syracuse.
305 BCE: Agathocles declares himself king of Syracuse.
288 BCE: Hicetus becomes tyrant of Syracuse.
270 BCE - 215 BCE: Hiero II is tyrant of Syracuse.
264 BCE - 241 BCE: First Punic War. Carthage cedes Sicily to Rome.
262 BCE: Rome attacks Agrigento.
250 BCE: Selinus on Sicily is abandoned.
213 BCE - 211 BCE: Roman commander Marcus Claudius Marcellus lays seige to and ultimately sacks Syracuse.
210 BCE: Rome attacks Agrigento.
201 BCE: Syracuse joins the Roman Republic, province of Sicily is formed.
189 CE: Septimius Severus is proconsul of Sicily. Birth of Geta, his second son.
535 CE: Belisarius conquers Sicily and Naples.