647 BCE - 629 BCE: Extensive collection of clay tablets acquired known as Ashurbanipal's Library at Nineveh.
597 BCE: Babylonian king Nebuchadnezar captures Jerusalem.
585 BCE: A battle between Media and Lydia broke off immediately as a result a total eclipse of the sun and the two armies made peace. The eclipse was successfully predicted by Thales of Miletus.
450 BCE: Parapegma star calendar invented in Greece by Meton and Euctemon.
450 BCE: First klepsydra - water timekeeping device - used in Athens.
420 BCE: Democritos develops an atomic theory of matter.
310 BCE - 290 BCE: Life of Greek astronomer and mathematician Aristarchus of Samos.
287 BCE - 212 BCE: Life of Archimedes, physician, mathematician and engineer.
275 BCE: Ctesibius invents first sophisticated multi-cogged water-clock.
270 BCE: Aristarchus of Samos proposes a heliocentric world view.
190 BCE - 120 BCE: Life of Hipparchus of Nicea, an ancient Greek mathematician, astronomer and geographer, regarded by many historians as a scientist of the highest quality and possibly the greatest astronomical genius among ancient Greeks.
159 BCE: First water-clock set up in Rome.
110 BCE - 50 BCE: Tower of The Winds by Andronicus constructed in Athens.
50 BCE: Antikythera instrument invented, an astronomical measuring device.