338 BCE: The first battle of Chaeronea. Philip of Macedon defeated the Greek alliance directed against him, led by Athens and Thebes.
87 BCE: The second battle of Chaeronea. The armies of Mithridates VI Eupator led by his general Archelaos, including a phalanx of freed slaves, was defeated by a Roman army led by Lucius Cornelius Sulla, in spite of the supremacy in cavalry of the Pontic army.
46 CE: The great greek historian and moralist, Plutarch, is born in Chaeronea.