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1100 CE - 1200 CE: The Valley of Mexico is first settled by migrating tribes (Chichimecs, Tepanecs, Mexica and Acolhua).
1345 CE - 1521 CE: The Aztec civilization flourishes in Mesoamerica.
1345 CE: Traditional date for the founding of the Aztec capital of Tenochtitlan on Lake Texcoco.
1350 CE - 1522 CE: The Tarascan civilization flourishes in Mesoamerica.
1375 CE - 1395 CE: Acamapichtli reigns as leader of the Aztecs.
1396 CE - 1417 CE: Huitzilihuitl reigns as leader of the Aztec empire.
1417 CE - 1426 CE: Chimalpopoca reigns as leader of the Aztec empire.
1418 CE: Texcoco is temporarily conquered by Mexica and Tepanec forces.
1427 CE: The Sun Stone depicting the ages of the five suns of Aztec mythology is carved and set up at Tenochtitlan.
1427 CE - 1440 CE: Itzcoatl reigns as leader of the Aztec empire.
1428 CE: The Triple Alliance is formed between Tenochtitlan, Texcoco and Tlacopan.
1431 CE: Netzahualcoyotl officially becomes tlatoani or leader of Texcoco.
1440 CE - 1469 CE: Motecuhzoma I reigns as leader of the Aztec empire.
1450 CE: The Aztecs establish a garrison at Mitla in the Oaxaca Valley.
1454 CE: New Fire Ceremony celebrated by the Aztecs.
1469 CE - 1481 CE: Axayacatl reigns as leader of the Aztec empire.
1473 CE: The Coyolxauhqui Stone is carved depicting the Aztec goddess Coyolxauhqui, dismembered by the god Huitzilopochtli.
1481 CE - 1486 CE: Tizoc reigns as leader of the Aztec empire.
1485 CE: The Stone of Tizoc is carved depicting the Aztec king Tizoc attacking warriors from the Matlatzinca.
1486 CE - 1502 CE: Ahuitzotl reigns as leader of the Aztec empire.
1487 CE: The Templo Mayor is completed at Tenochtitlan and inaugurated with the sacrifice of 20,000 captives.
1494 CE: Aztec leader Ahuitzotl conquers the central valleys of Oaxaca.
1502 CE - 1520 CE: Motecuhzoma II reigns as leader of the Aztec empire.
1507 CE: New Fire Ceremony celebrated by the Aztecs.
1507 CE: The Throne of Motecuhzoma II is carved. Also known as the Monument of Sacred War.
1519 CE: Motecuhzoma II receives Cortes at the Aztec capital Tenochtitlan.
1520 CE: Cuitlahuac is briefly the successor to Motecuhzoma II as leader of the Aztec empire.
1520 CE: Death of Aztec ruler Motecuhzoma II.
1521 CE: Texcoco provided ships and men to aide the Spanish siege of Tenochtitlan.
1521 CE - 1525 CE: Cuauhtemoc reigns as leader of the Aztec empire
1521 CE: The Aztec capital of Tenochtitlan falls into the hands of spanish forces led by Cortés.